An apartment building was one of the places affected in Ukraine's second largest city, where at least 16 people were injured.
At least three people were killed and 16 injured after Russian missiles hit at least three sites, including a five-story apartment building in Kharkiv, Ukraine's second-largest city.
Regional Governor Oleh Syniehubov said the missiles, all of them S-300s, also hit a shop in a three-story building and a clothing factory in the city's Novobazarskyi district.
Syniehubov said the attacks were of the “double-tap” type, with a second attack hitting a site shortly after the first at a time when emergency teams are usually working.
The attack took place around midnight local time (21:00 GMT).
Syniehubov said the injured included at least two children, as well as an emergency doctor, and warned that residents could be trapped under the building's rubble.
“The third, fourth and fifth floors were destroyed, the stairs were destroyed, the facades were destroyed,” Kharkiv Mayor Ihor Terekhov told public broadcaster Suspilne, describing the damage.
Kharkiv police chief Volodymyr Tymoshko told Suspilne he expected the death toll to rise given the magnitude of the destruction and the likelihood of shrapnel injuries.
Kharkiv, which is located not far from the border with Russia's Belgorod region, has come under renewed attacks in recent weeks. Some 17 people were killed last weekend when Russia, which launched an offensive in the region earlier this month, bombed a hardware hypermarket in the city.
Kharkiv, which had a population of around 1.5 million people before the war, resisted Russian advances in the first weeks of its February 2022 invasion.
Moscow says it does not deliberately target civilians.
US officials revealed on Thursday that President Joe Biden had lifted restrictions on Ukraine using US-supplied weapons against targets on Russian territory, saying they could be used against Russian troops and military sites in areas bordering the Kharkiv region.