The Premier League announced the match schedule for the 2024-25 season on Tuesday, with defending champions Manchester City beginning their title defense at Stamford Bridge against Chelsea on August 18 in what will be Enzo Maresca's first game for the West London club.
The first clash between last season's top two, City and Arsenal, will take place on September 21 at the Etihad Stadium, while the return match at the Emirates will be on February 1.
Manchester United will face City at the Etihad on December 14 and at Old Trafford on April 5, while United will head to Anfield to play Liverpool on January 4 after hosting them in just the third match of the campaign on August 31.
United will host Fulham on Friday, August 16 in the first match of the Premier League season.
Arne Slot's Liverpool tenure begins with a trip to Ipswich Town's Portman Road, which will host the Premier League for the first time since relegation in 2002.
Life in the top flight doesn't get much easier for Kieran McKenna's side as they head to the Etihad for their first away game on August 24.
Promoted teams Leicester City and Southampton begin their seasons with Tottenham Hotspur at home and a trip to Newcastle United respectively.
Guardiola's City are seeking an unprecedented fifth consecutive title in 2024-25, having won the league in six of the last seven seasons.
Meanwhile, Mikel Arteta's Arsenal are seeking their first title since the “Invincibles” 2003-04 season.