Find out who is absent through injury, who is in a race against time to prove their fitness and who has been ruled out through suspension for the next round of Premier League matches.
And as you plan your fantasy team for the upcoming game week, check out the expected XIs for all 20 clubs.
Positions: GGoalkeeper (GK), Defender (D), Left Back (LB), Right Back (RB), Center Back (CB), Midfielder (M), Defensive Midfielder (DM), Central Midfielder (CM), Left Midfielder (LM), Right Midfield (RM), Attacking Midfield (AM), Left Winger (LW), Right Winger (RW), Forward (F), Left Forward (FWL), Right Forward (FWR), Forward (ST)
(All expected XI and injury news powered by Rotowire, subject to updates.)
Everton-Aston Villa
Goodison Park
Wednesday, 7:30 p.m. GMT / 2:30 p.m. ET
Latest Everton team news
Expected lineup:
G.K. Jordan Pickford
pound Vitaliy Mykolenko | C.B. Jarrad Branthwaite | C.B. James Tarkowski | R.B. ashley young
DM Idrissa Gueye | DM Orel Mangala
L.W. Iliman Ndiaye | AM Abdoulaye Doucouré | R.W. Jack Harrison
STREET Dominic Calvert-Lewin
Injury/Suspension Updates:
Armando Broja, F, ankle, OUTSIDE, estimated return January 25
Dominic Calvert-Lewin, F, ankle, DOUBT
Seamus Coleman, D, undisclosed, DOUBT
James Garner, M, back, OUTSIDE, estimated return January 19
Tim Iroegbunam, M, foot, OUTSIDE, estimated return January 19
Dwight McNeil, M/F, knee, OUTSIDE, estimated return January 19
Youssef Chermiti, F, undisclosed, OUTSIDE, estimated return February 1
Latest Aston Villa team news
Expected lineup:
G.K. Emiliano Martínez
pound Lucas Digne | C.B. Ezri Konsa | C.B. Tyrone Mings | R.B. Matty cash
DM Youri Tielemans | DM Boubacar Kamara
L.W. Jacob Ramsey | AM Morgan Rogers | R.W. Leon Bailey
STREET Olivia Watkins
Injury/Suspension Updates:
Ross Barkley, M, calf, OUTSIDE, estimated return January 29
Emiliano Martínez, G, undisclosed, DOUBT
John McGinn, M, hamstring, OUTSIDE, estimated return January 29
Diego Carlos, D, foot, OUTSIDE, estimated return January 18
Pau Torres, D, foot, OUTSIDE, estimated return March 15
Leicester City-Crystal Palace
King Power Stadium
Wednesday, 7:30 p.m. GMT / 2:30 p.m. ET
Latest news from the Leicester City team
Expected lineup:
G.K. Jakub Stolarczyk
pound Victor Kristiansen | C.B. Conor Coady | C.B. Jannik Vestergaard | R.B. James Justino
DM Boubakary Soumaré | DM Harry winks
L.W. Stephy Mavididi | AM Bilal El Khannouss | R.W. Jordan Ayew
STREET Jaime Vardy
Injury/Suspension Updates:
Odsonne Édouard, F, undisclosed, DOUBT
Fatawu Issahaku, F, knee, OUTSIDE, estimated return August 25
Mads Hermansen, G, groin, OUTSIDE, estimated return January 26
Wilfred Ndidi, M, hamstring, OUTSIDE, estimated return January 26
Ricardo Pereira, D, hamstring, OUTSIDE, estimated return March 15
Jannik Vestergaard, D, hamstring, DOUBT
Latest Crystal Palace team news
Expected lineup:
G.K. Dean Henderson
C.B. Trevoh Chalobah | C.B. Marc Guéhi | C.B. Maxence Lacroix
L.M. Tyrick Mitchell | CENTIMETER Will Hughes | CENTIMETER Jefferson Lerma | RM Daniel Muñoz
AM Eberechi Eze | AM Ismaila Sarr
STREET Jean-Philippe Mateta
Injury/Suspension Updates:
Matheus França, M/M, groin, OUTSIDE, estimated return January 26
Will Hughes, M, foot, DOUBT
Adam Wharton, M, groin, OUTSIDE, estimated return February 15
Newcastle United-Wolverhampton Wanderers
St. James Park
Wednesday, 7:30 p.m. GMT / 2:30 p.m. ET
Latest Newcastle United team news
Expected lineup:
G.K. Martin Dubravka
pound Lewis Lounge | C.B. Sven Botman | C.B. Dan burn | R.B. Valentino Livramento
CENTIMETER Joelinton | CENTIMETER Bruno Guimaraes | CENTIMETER Sandro Tonali
F.W.L. Antonio Gordon | STREET Alejandro Isak | FWR Jacob Murphy
Injury/Suspension Updates:
Harvey Barnes, F/M, thigh, OUTSIDE, estimated return February 15
Alexander Isak, F, hamstring, DOUBT
Emil Krafth, D, clavicle, OUTSIDE, estimated return January 25
Jamaal Lascelles, D, knee, OUTSIDE, estimated return January 25
Nick Pope, G, knee, OUTSIDE, estimated return January 18
Callum Wilson, F, hamstring, OUTSIDE, estimated return February 1
Latest Wolverhampton Wanderers team news
Expected lineup:
G.K. Jose Sa
C.B. Emmanuel Agbadou | C.B. Santiago Bueno | C.B. Matt Doherty
L.M. Rayan Aït-Nouri | CENTIMETER João Gomes | CENTIMETER Andre | RM pedro lima
AM Gonçalo Guedes | AM Matheus Cunha
STREET Jørgen Strand Larsen
Injury/Suspension Updates:
Craig Dawson, D, calf, DOUBT
Toti Gomes, D, hamstring, OUTSIDE, estimated return January 25
Enso González, F/M, knee, OUTSIDE, estimated return May. 3
Sasa Kalajdzic, F, knee, OUTSIDE, estimated return February 16
Mario Lemina, M, undisclosed, DOUBT
Yerson Mosquera, D, knee, OUTSIDE, estimated return August 15
Nélson Semedo, M/D, hamstring, DOUBT
Boubacar Traoré, M, knee, OUTSIDE, estimated return February 16
Arsenal-Tottenham Hotspur
Emirates Stadium
Wednesday, 8 pm GMT / 3 pm Eastern Time
Latest Arsenal team news
Expected lineup:
G.K. David Rayá
pound Myles Lewis-Skelly | C.B. Gabriel Magalhães | C.B. Guillermo Saliba | R.B. Jurrien Madera
CENTIMETER Martin Ødegaard | CENTIMETER Mikel Merino | CENTIMETER Declan Rice
F.W.L. Gabriel Martinelli | STREET Kai Havertz | FWR Leandro Trossard
Injury/Suspension Updates:
Riccardo Calafiori, D, strain, DOUBT
Gabriel Jesus, F, knee, OUTSIDE, estimated return October 1
Ethan Nwaneri, M, strain, OUTSIDE, estimated return January 25
Bukayo Saka, F/M, hamstring, OUTSIDE, estimated return March 8
Jurriën Timber, D, undisclosed, DOUBT
Takehiro Tomiyasu, D, knee, OUTSIDE, estimated return January 25
Ben White, D, knee, OUTSIDE, estimated return January 29
Latest news from the Tottenham Hotspur team
Expected lineup:
G.K. Antonin Kinsky
pound Djed Spence | C.B. Radu Dragusin | C.B. Archie Gray | R.B. Pedro Porro
DM Lucas Bergvall | DM Pape Matar Sarr
L.W. Son Heung-Min | AM Dejan Kulusevski | R.W. Brennan Johnson
STREET Dominic Solanke
Injury/Suspension Updates:
Rodrigo Bentancur, M, concussion, OUTSIDE, estimated return January 26
Ben Davies, D, hamstring, OUTSIDE, estimated return January 26
Richarlison, F, hamstring, DOUBT
Destiny Udogie, D, hamstring, OUTSIDE, estimated return February 25
Fraser Forster, G, illness, DOUBT
Wilson Odobert, F/M, hamstring, OUTSIDE, estimated return February 15
Cristian Romero, D, quadriceps, OUTSIDE, estimated return January 26
Micky van de Ven, D, hamstring, OUTSIDE, estimated return January 26
Guglielmo Vicario, G, ankle, OUTSIDE, estimated return February 25
Timo Werner, F/M, hamstring, OUTSIDE, estimated return January 23
Ipswich Town v Brighton & Hove Albion
Portmán Highway
Thursday, 19:30 GMT / 14:30 ET
Latest Ipswich Town team news
Expected lineup:
G.K. christian walton
pound Leif Davis | C.B. Jacob's Greaves | C.B. Dara O'Shea | C.B. Lucas Woolfenden | R.B. Ben Johnson
L.M. Nathan Broadhead | CENTIMETER Jens Cattle | CENTIMETER Sam Morsi | RM Wes Burns
STREET Liam Delap
Injury/Suspension Updates:
Conor Chaplin, f/m, knee, OUTSIDE, estimated return January 25
Omari Hutchinson, M/F, groin, OUTSIDE, estimated return January 25
Chiedozie Ogbene, F/M, Achilles, OUTSIDE, estimated return May. 3
Sammie Szmodics, F/M, strain, DOUBT
Axel Tuanzebe, D, hamstring, OUTSIDE, estimated return February 1
Latest Brighton & Hove Albion team news
Expected lineup:
G.K. Bart Verbruggen
pound Pervis Estupiñán | C.B. Lewis Mate | C.B. Jan Paul van Hecke | R.B. Joel Veltman
DM Yasín Ayari | DM Carlos Baleba
L.W. Kaoru Mitoma | AM Julio Enciso | R.W. Brajan Gruda
STREET Danny Welbeck
Injury/Suspension Updates:
Lewis Dunk, D, calf, DOUBT
Evan Ferguson, F, ankle, OUTSIDE, estimated return January 25
Jack Hinshelwood, M/D, knee, DOUBT
Igor Julio, D, hamstring, OUTSIDE, estimated return June 1
João Pedro, F/M, ankle, DOUBT
Ferdi Kadioglu, M/D, toe, OUTSIDE, estimated return February 14
James Milner, M/D, hamstring, OUTSIDE, estimated return January 25
Yankuba Minteh, F, hamstring, DOUBT
Georginio Rutter, F, hamstring, DOUBT
Mats Wieffer, M, undisclosed, OUTSIDE, estimated return January 25
Manchester United-Southampton
Old Trafford
Thursday, 8 pm GMT / 3 pm ET
Latest Manchester United team news
Expected lineup:
G.K. André Onana
C.B. Matthijs de Ligt | C.B. Harry Maguire C.B. Lisandro Martinez
L.M. Tyrell Malacia | CENTIMETER Kobbie Mainoo | CENTIMETER Manuel Ugarte | RM Noussair Mazraoui
AM Amad Diallo | AM Bruno Fernandez
STREET Rasmus Hojlund
Injury/Suspension Updates:
Diogo Dalot, M/D, suspension, will return on January 19
Victor Lindelöf, D, concussion, DOUBT
Mason Mount, F/M, strain, DOUBT
Marcus Rashford, F, illness, DOUBT
Luke Shaw, D, calf, OUTSIDE, estimated return January 26
Latest Southampton team news
Expected lineup:
G.K. Aaron Ramsdale
C.B. Jan Bednarek | C.B. Taylor Harwood-Bellis | C.B. nathan wood
L.M. Kyle Walker-Peters | CENTIMETER Flynn Downes | CENTIMETER Lesley Ugochukwu | RM Yukinari Sugawara
AM Tyler Dibling | AM Mateo Fernandes
STREET Pablo Onuachu
Injury/Suspension Updates:
Gavin Bazunu, G, Achilles, OUTSIDE, estimated return February 15
Flynn Downes, M, undisclosed, DOUBT
Jack Stephens, D, undisclosed, OUTSIDE, estimated return February 1
Ross Stewart, F, calf, OUTSIDE, estimated return January 25
