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They may have gained popularity for diabetes and weight loss, but GLP-1 medications such as Ozempic and Wogovy have been related to constantly expanding health benefits.
In fact, some doctors, including Dr. Terry Dubrow, a plastic surgeon and TV personality based in Newport Beach, California, recommend that everyone drinks a low daily dose, even if they do not need to lose weight.
Dubrow spoke on camera with Fox News Digital about the benefits of “microdosos” these medications. (See the video at the top of this article).
How the LPG-1 work
GLP-1 receiver agonists work imitating a hormone called Glucagon-like peptide, which is released from the intestine after eating.
Drugs help regulate blood sugar, reduce the speed of stomach emptying and decrease appetite, and it has also been shown that they reduce the risk of heart disease.
Dr. Terry Dubrow, a plastic surgeon and television personality based in Newport Beach, California, recommends that everyone take a low daily dose of a LPG-1, even if they do not need to lose weight. (Terry Dubrow)
“Sugar is the enemy, and these drugs affect your blood sugar,” Dubrow told Fox News Digital. “They affect the way insulin reacts.”
LPG-1 help insulin to move glucose (sugar) outside the bloodstream and body cells, where it can be used to obtain energy or store, said the doctor. Medications also help prevent inflammation and damage that sugar can cause in blood vessels, nerves and organs.
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“I don't think anyone would argue that if there were a way to manipulate the amount of sugar and inflammation to which your body is exposed, that is something we want to support us. And that is exactly what these drugs do,” Dubrow added.
In addition to regulating blood sugar and triggering weight loss, LPG-1 have also been approved to reduce the risk of cardiovascular events and kidney disease in certain patients.
“I have never seen that a drug in the history of medicine is on such a fast path to approval.”
“Even if you have no overweight, being taking these GLP-1 medications … helps minimize and prevent repeated recurrent heart attack,” Dubrow said.
Semaglutida was also recently approved for puree (steatohepatitis associated with metabolic dysfunction), an inflammatory form of fatty liver disease.
Dubrow spoke on camera with Fox News Digital about the benefits of GLP-1 medications. (Fox News Digital)
LPG-1 are also being studied to obtain possible cognitive benefits in Parkinson's patients.
“I have never seen that a drug in the history of medicine is on such a fast path to approval,” Dubrow said.
The case of microdosis
Together with other experts, Dubrow is a microdosis defender, which is where people drink low and constant LPG-1 doses every day, even if they do not need them for diabetes or obesity.
While diabetes patients take doses that increase every four weeks, microposition involves using a low level dose that does not increase.
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A younger population in Tiktok has concentrated on microosition, Dubrow said, and believes everyone should do so.
“I am obsessed with the concept of microdososis,” he said. “I think that perhaps half of the initial dose for diabetes is the way to follow, and probably does not need it every seven days, it is probably every 10 days, just to modulate the amount of blood sugar.”
“Even if you have no overweight, being taking these GLP-1 medications … helps minimize and prevent repeated recurrent heart attack,” Dubrow said. (Istock)
The doctor said there are still many unknowns with GLP-1 medications.
“We are discovering now how to use these drugs for different indications, for different reasons,” he said. “We are learning while we are using it.”
“I am obsessed with the concept of microdososis.”
As with other drugs, such as Botox, Dubrow said there is a bit of “human experimentation” at stake.
“We are discovering it and we are teaching the medical profession how to do it. Patients tell us how to use these medications.”
Potential risks
GLP-1 medications have been linked to several potential risks. The most frequent are gastrointestinal problems, such as nausea and vomiting.
Others have reported a higher risk of pancreatitis, muscle loss and thyroid tumors.
“I read every study on these drugs, and I can tell you that it is very clear that they do not cause pancreatites,” Dubrow said.
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“In fact, if you really look at the populations that have been using it, pancreatitis is less in those populations.”
Dubrow confirmed, however, that the medicine has been related to a higher risk of very rare medullary cancer of the thyroid.
Those who experience severe SDG-1 side effects should talk to a doctor, Dubrow advised. (Istock)
“If you have a family history of that, it is a contraindication for you using these drugs,” he said.
Regarding digestive side effects, the doctor said that medications slow down the gastrointestinal tract, but it has been shown that the body fits that over time.
“These particular drugs are natural hormones that occur in our small intestine, and you get used to side effects. They leave.”
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The severity of side effects is linked to the amount of dose, Dubrow said.
“The low dose, particularly the microdosa, really has a low propensity towards constipation, nausea, potential diarrhea, ERG (reflux),” he said. “I think these side effects are less significant for people who are microdosa.”
To counteract the risk of muscle loss, Dubrow recommends increasing protein intake and incorporating resistance training as a central component of an exercise routine.
Those who experience serious side effects should talk to a doctor, he advised.
The use of the LPG-1 label, as for microdosis, is common, said Dubrow: “But finding a doctor willing to prescribe can be difficult.” (Istock)
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When Fox News Digital was contacted, GLP-1 drug manufacturers warned against the microdose of the products.
“Lilly has no data on the benefits or risks of Zepbound and Mounjaro microdose,” said an Eli Lilly spokesman, GLP-1 Mounjaro and Zepbund drug manufacturer. “Both autoinjectors and Zepbound roads are approved only for one use: the dose division or 'microdosis' is not contemplated by the FDA label. As such, the out of Zepbound and Mounjaro's label can pose patient safety risks.”
“Outside of Zepbound and Mounjaro's label can represent patient safety risks.”
Novo Nordisk, manufacturer of Ozempic and Wegovy, said it does not approve the “misuse” of its products.
“It is important to understand that for Wogovy, only the doses marked on single -use fixed dose pens (0.25, 0.5, 1.0, 1.7 and 2.4 mg) are approved for use and represent a real medicine approved by the FDA,” said a digital Fox News spokesperson. “The initial Wegovy® dose is 0.25 mg once a week, and the dose will gradually increase every four weeks. Patients should work with their health professional to select 1.7 mg or 2.4 mg for the maintenance dose.”
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“It is also important to keep in mind that the authentic injectable pen is designed as a single -use pen, the dose is already established, and should not be altered or manipulated, and the pen must be arranged after a use.”
“Ozempic is a multiple -use pen with a pen and multiple needles,” added the spokesman.
Access to LPG-1
Dubrow said that he is not worried about supply problems amid the growing popularity of LPG-1, since the main pharmaceutical companies have resources to “expand” to meet demand.
The use of the LPG-1 label, as for microdosis, is common, said Dubrow: “But finding a doctor willing to prescribe can be difficult.”
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The doctor warned against the purchase of these drugs from online markets, which he was referring to as the “Wild Wild West.”
“It is difficult to find these online drugs by aggravating pharmacies, because they are essentially becoming rebels, it is illegal. They do not allow it to do it,” he warned.
“These drugs are natural hormones that occur in our small intestine, and you get used to side effects.”
“So, if you get it from rebel pharmacies that are not allowed or willing to bend the rules, what is it? You don't know what you are getting.”
“It can be an adult and strange version that has side effects or that is not effective.”
Looking to the future
There are several next -generation developing medications that combine multiple hormonal routes, Dubrow said.
“I predict in five years, we will have a pill … designed to manipulate hunger and insulin resistance,” he predicted.
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In general, said Dubrow, the LPG-1 are “here to stay.”
“They will simply improve, and we will learn to use them in a more appropriate and clinically effective way,” he said. “So they fake your seat belt. If you are not in them now, you will be later.”
