Christina Applegate describes 'fatalistic' depression after MS diagnosis: 'I don't enjoy living'


Christina Applegate has opened up about her struggle with depression after her multiple sclerosis diagnosis and said her mental health deteriorated to the point where it started to scare her.

Speaking with co-host Jamie-Lynn Sigler on her podcast MessyIn , recorded in January but released Tuesday, the actor said he felt “a real, fucking depression, like a real depression, which scares me a little bit because it feels really fatalistic. It feels really at the end.”

“I don't mean that, but right now I'm trapped in this darkness that I haven't felt in probably 20-something years,” she said. “I don't enjoy living. I don't enjoy it. “I don't enjoy things anymore.”

Sigler, who was diagnosed with multiple sclerosis, or MS, while working at The sopranos More than 20 years ago, he urged Applegate to “give himself a chance.”

“It's very difficult to live in a disabled body,” he said.

“It's very difficult. I won't take it away from you and I'm right there with you. I can't let you give up. I can't. I need you to do it for me.”

Jamie-Lynn Sigler and Christina Applegate
Jamie-Lynn Sigler and Christina Applegate (Good morning America, ABC)

Applegate went on to say that she called her therapist to schedule an appointment for the following week “which was a big deal for me.”

He dead to me Star said therapy was difficult for her because she was afraid she wouldn't be able to stop crying and that she continued to deal with her diagnosis through self-hatred.

She also talked about her appearance at this year's Emmy Awards, where she joked with the audience as they applauded her, saying, “You're totally embarrassing me, disabled, by standing up. Alright!”

“I've avoided therapy since I was diagnosed because I'm so afraid of starting to cry and not being able to stop crying,” she said.

“I'm very afraid that those floodgates will open and I won't be able to stop.”

At the Emmys appearance, which Applegate referred to as “the TV thing,” she talked about the toll it took on her body.

“That was like the hardest day of my life. It started at 11 in the morning and I didn't get home until 9:30,” Applegate said.

“I think I slept two days in a row. “I couldn’t function.”

Christina Applegate speaks onstage at the 75th Primetime Emmy Awards in Los Angeles on January 15, 2024.
Christina Applegate speaks onstage at the 75th Primetime Emmy Awards in Los Angeles on January 15, 2024. (getty)

Applegate explained how multiple sclerosis manifests differently in people. She talked about the 30 lesions on her brain and how other people have them elsewhere.

“The biggest one is behind my right eye, so my right eye hurts a lot,” he said.

“What it does is simply affect the nervous system. So we all have the problem of mobility. It is different per person. The way it manifests in Jamie is very different than how it manifests in me.

“This is a forever disease for us.

“Before B cell treatments, people simply died from it. That is why we are now prolonging life with these treatments. That doesn't mean I'll be here in 10 years, I don't know. That's what's scary about MS. There is no end.

“It's a progressive disease and it gets progressively worse.”

In August 2021, Applegate revealed that she had been diagnosed with multiple sclerosis a few months earlier and that the Netflix production dead to me It had to be stopped for five months when treatment began.

However, during an appearance on Good morning america In March, Applegate said she believed that although she received her official diagnosis in 2021, she had probably had it “six or seven years” earlier.

“I noticed, especially in the first season, that we were filming and my leg would bend,” he said, referring to dead to me.

“I really put it off because I'm tired, or I'm dehydrated, or it's the weather. Then nothing happened for months and I didn't pay attention.”

If you are experiencing feelings of distress or are having difficulty coping, you can speak to the Samaritans, confidentially, on 116 123 (UK and ROI), email [email protected] or visit the Samaritans website to find details of your nearest branch. If you reside in the US and you or someone you know needs mental health assistance right now, please call or text 988, or visit 988lifeline.org to access the 988 Suicide and Crisis Lifeline online chat. This is a free and confidential crisis hotline that is available to everyone 24 hours a day, seven days a week.

If you are in another country, you can go to www.befrienders.org to find a helpline near you.

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