Mexico beat the United States for the second time in its history, with goals from Lizbeth Ovalle and Mayra Pelayo for a 2-0 victory Monday night in the CONCACAF Women's Gold Cup.
The United States entered the game 40-1-1 against its rival, with its only previous loss coming a 2-1 decision during Women's World Cup qualifying in 2010.
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It was the United States' first loss under interim coach Twila Kilgore, who took over after the team's dramatic elimination from the Women's World Cup last summer in the round of 16. Emma Hayes will replace Kilgore this spring.
Mexico, which failed to qualify for last year's World Cup, finished atop Group A in the Gold Cup, while the United States finished second. Both teams advanced to the knockout round.
Ovalle, who plays for Tigres, put Mexico ahead in the 28th minute. American defender Becky Sauerbrunn tried to defend Ovalle but she kicked the ball. Ovalle launched a shot over goalkeeper Alyssa Naeher and two American defenders and into the net.
It was the first goal conceded by the United States to a CONCACAF opponent in 33 games.
Mexico was about to score again in first-half stoppage time, but a long-range shot by Karla Nieto hit the crossbar.
Kiana Palacios had a good chance to give Mexico the lead, but her shot hit defender Abby Dahlkemper and deflected.
Pelayo scored from distance in extra time and Mexico's players celebrated wildly on the field.
The United States saw the success of its teenagers in the first two games of the tournament. Olivia Moultrie, 18, scored twice in a 5-0 win over the Dominican Republic and Jaedyn Shaw, 19, scored a pair in a 4-0 win over Argentina.
This is the first Women's Gold Cap, created to provide women's teams in the CONCACAF region with more competitive matches. Twelve teams played group stage games in three cities: Carson, San Diego and Houston.
Argentina beat the Dominican Republic 3-0 earlier Monday in Group A.