What is Cushing's syndrome? The hormonal disorder that Amy Schumer was diagnosed with


Amy Schumer has revealed that she has been diagnosed with Cushing's syndrome after receiving numerous comments about her appearance during her life and beth press tour.

In the “News Not Noise” letter published on February 23, Jessica Yellin revealed that the famous comedian had “exogenous Cushing syndrome, caused by receiving high-dose steroid injections.”

Cushing's syndrome occurs when the body produces too much of the hormone cortisol. “This may be due to the body producing too much cortisol or taking medications called glucocorticoids, which affect the body in the same way as cortisol,” according to the Mayo Clinic.

There are two types of disorder: exogenous and endogenous. Exogenous Cushing's syndrome occurs due to factors external to the body, while endogenous Cushing's syndrome occurs due to factors internal to the body. According to a report from the Endocrine Society, the symptoms resulting from the disorder are the same regardless of the type. However, endogenous is rarer and can potentially be caused by a tumor that produces too much cortisol.

Symptoms may include weight gain on the back and face, stretch marks (specifically on the stomach, hips, breasts, arms, and thighs), skin that breaks easily, acne, slow skin healing, and a “lump of fat between the shoulders,” according to the Mayo Clinic.

Hirsutism, the growth of thick, dark hair, is a common symptom seen in women suffering from Cushing's syndrome. Additionally, women with this disorder may stop having their period or their period may become less frequent.

Men with Cushing syndrome may experience a lower sexual desire, problems with sexual activity, and reduced fertility.

Other common symptoms for both men and women are increased tiredness, muscle weakness, headaches, infections, bone loss, high blood pressure, and darkening of the skin.

Speaking to Yellin, Schumer detailed how he felt physically. First, he pointed out how her diagnosis came about.

“While doing on-camera press for my Hulu show, I was also in MRI machines for four hours straight, with my veins closed from the amount of blood drawn and thinking I might not be around to see my son grow up.” . ”said the 42-year-old actress.

“So finding out that I have the type of Cushing's that will just clear up on its own and that I'm healthy was the best news imaginable. “It’s been a crazy couple of weeks for me and my family,” she continued.

Overall, Schumer said she felt “reborn” after learning the diagnosis and that it is curable.

Cushing's syndrome is completely treatable and can be cured. The medications include “ketoconazole, osilodrostat (Isturisa), mitotane (Lysodren), levoketoconazole (Recorlev), and metyrapone (Metopirone),” according to the Mayo Clinic.

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