A flight bound for London's Heathrow Airport, likely carrying stranded British citizens, departed Abu Dhabi.
Etihad Airways flight EY67 is expected to land at 7.14pm at Terminal 4 at West London Airport.
It was one of 15 Etihad Airways flights that departed Abu Dhabi in a three-hour period.
The flights “will likely help get out transit passengers who have been stuck there since the start of the conflict,” flight tracking company Flightradar24 said.
Dubai-based Emirates airline said it will resume operations with “a limited number of flights” on Monday evening.
He said his priority is to “serve customers with previous reservations.”
The General Authority of Civil Aviation of the United Arab Emirates said in its X account that certain flights are already operating.
He said passengers should not go to airports until they have been contacted and notified of their flight times and details.
Foreign Minister Yvette Cooper indicated that 102,000 British citizens have registered their presence in the region.
He said a total of about 300,000 British citizens are in Gulf countries targeted by Iran.
British citizens are advised to follow guidance from local authorities and monitor Foreign Office travel advice, which officials expect to change quickly.
Those in Bahrain, Israel, Kuwait, Palestine, Qatar and the United Arab Emirates (UAE) have been urged to register their presence with the Ministry of Foreign Affairs online.
The Government has used the registration system before to provide urgent updates to people affected by international crises, but it has not previously needed to deal with so many people in so many different countries.
Cooper told BBC Breakfast: “The latest figure I have from this morning is that we have 102,000 people who have responded to our proposal to ask them to register their presence so that we know where they are, particularly in these Gulf countries that have been attacked, so that we know where they are and we can get information to them quickly.
“In many of these countries airspace is currently closed due to Iranian attacks.
“This is obviously very stressful for people because we are talking about a lot of people who are on vacation, who were transit passengers who were passing through or people on business visits to the region and who we want to make sure can return home safely.”
It is understood that any repatriation of UK citizens would likely be organized by the Foreign Office, with one potential route involving people traveling by land to Saudi Arabia from where they could board flights.
Airspace closures in the Middle East have led to the suspension of several commercial flights since the attacks began on Saturday.
More than a third of flights scheduled to depart from the UK to the region on Monday were cancelled.
Analytics firm Cirium said 49 of 144 flights were cancelled.
British Airways said it is “closely monitoring the situation” and has canceled “a number of our flights to the Middle East.”
Virgin Atlantic canceled two flights to Heathrow on Monday, one from Dubai (UAE) and Riyadh (Saudi Arabia), while others were diverted.
